IN VITRO : Novel potent apoptosis inducer in Glioblastoma multiforme (GBM; grade IV astrocytoma) cancer stem cells (CSCs), inducing caspase 1-dependent apoptosis by binding to receptor-interacting protein kinase 2 (RIPK2) and acting as a molecular switch, which reduces the formation of a prosurvival RIPK2/TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex
IN VITRO : Apoptosis inducer is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. significantly reduced the gal-1 protein level. Apoptosis inducer is also a PET imaging agent.