Name : 5, 16-PREGNADIEN-3β-OL-20-ONE ACETATE, 20-OXIME
CAS Number : 2174-13-2
Molecular Formula : C₂₃H₃₃NO₃
Molecular Weight : 371.51
Purity : 98%
Appearance : powder
Applications : Building block , Laboratory chemical , Compound is subject for research & development use only as organic experimental building block. STRICTLY not for human or animal use.
IN VITRO : Novel potent apoptosis inducer in Glioblastoma multiforme (GBM; grade IV astrocytoma) cancer stem cells (CSCs), inducing caspase 1-dependent apoptosis by binding to receptor-interacting protein kinase 2 (RIPK2) and acting as a molecular switch, which reduces the formation of a prosurvival RIPK2/TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex
Corey–Itsuno reducing agent, Corey–Bakshi–Shibata (CBS) reduction agent enantioselective reducing agent for Ketones to Alcohol
S-catalyst makes R'-OH in high yield 99% ee (R- Enantiomer)
Reagent DPPA is versatile reagent for Curtius rearrangement to convert Carboxylic acids to their coresponding derivates eg :
Amines, Isocyanates, Urea derivates , Carbamates