1-Benzyl-3-(4-fluorobenzyl)-2-methyl-4,9-dioxo-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium chloride , cRIPGBM , CAS: 2361988-76-1
IN VITRO : Novel potent apoptosis inducer in Glioblastoma multiforme (GBM; grade IV astrocytoma) cancer stem cells (CSCs), inducing caspase 1-dependent apoptosis by binding to receptor-interacting protein kinase 2 (RIPK2) and acting as a molecular switch, which reduces the formation of a prosurvival RIPK2/TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex
![1-Benzyl-3-(4-fluorobenzyl)-2-methyl-4,9-dioxo-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium chloride , cRIPGBM , CAS: 2361988-76-1](/media/SlikeIT/marvinjs-output%20-%202022-07-22T151022.675.png)
Article number : IL-AI
Name : 1-Benzyl-3-(4-fluorobenzyl)-2-methyl-4,9-dioxo-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium chloride
CAS Number : 2361988-76-1
Molecular Formula : C26H20FN2O2+
Molecular Weight : 411.45
Purity : 98%
Appearance : powder
Applications : Building block , Laboratory chemical , Compound is subject for research & development use only as organic experimental building block. STRICTLY not for human or animal use.
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