Name : 1-(1,3-benzodioxol-5-yl)-2-iodopropan-1-one
CAS Number : N/A
Molecular Formula : C10H9IO3
Molecular Weight : 304.1
Purity : 98%
Appearance : powder
Applications : Building block , Laboratory chemical , Compound is subject for research & development use only as organic experimental building block. STRICTLY not for human or animal use.
IN VITRO : Novel potent apoptosis inducer in Glioblastoma multiforme (GBM; grade IV astrocytoma) cancer stem cells (CSCs), inducing caspase 1-dependent apoptosis by binding to receptor-interacting protein kinase 2 (RIPK2) and acting as a molecular switch, which reduces the formation of a prosurvival RIPK2/TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex
Reagent DPPA is versatile reagent for Curtius rearrangement to convert Carboxylic acids to their coresponding derivates eg :
Amines, Isocyanates, Urea derivates , Carbamates