IN VITRO : Novel potent apoptosis inducer in Glioblastoma multiforme (GBM; grade IV astrocytoma) cancer stem cells (CSCs), inducing caspase 1-dependent apoptosis by binding to receptor-interacting protein kinase 2 (RIPK2) and acting as a molecular switch, which reduces the formation of a prosurvival RIPK2/TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex
Corey–Itsuno reducing agent, Corey–Bakshi–Shibata (CBS) reduction agent enantioselective reducing agent for Ketones to Alcohol
S-catalyst makes R'-OH in high yield 99% ee (R- Enantiomer)